Yesterday I had increasing significant bouts of diarrhea as the afternoon rolled on here at Nuevo Rancho Lake. I'm not sure why, as my GI had been fairly quiet the last couple of days, and we're well away from Shedding Day. This may have been as simple as traveler's tummy. But by the evening, it was clear to me that I was not going to have an easy night of it the way things were going.
So with great reluctance I took a Lomotil (diphenoxylate/atropine).
One of the things they tell you in chemotherapy is to control diarrhea immediately. The concern, of course, is massive fluid loss in an already stressed out system. The instructions I have been given in the past, recently repeated, were to take an Imodium (loperamide) at the first incident of diarrhea, then continue to take an addition Imodium every time it recurs until the incidents stop.
In my case, I react very poorly to Imodium, and even a single pill can painfully constipate me for 36 hours or more, leading to even more dreadful diarrhea and other GI problems when it wears off than I had in the first place. That cure is definitely worse than the symptom it's meant to address.
Lomotil seems to slow me down without giving me a concrete enema the way Imodium does. My GI restarts about 12 hours later in a fairly sane manner.
But here's what I've never understood about those instructions. The diarrhea always wins. Whatever's in there trying to get out doesn't magically go away because we stoppered the colorectal system for a day. The massive shedding of disrupted stomach cells and dying bone marrow from chemo goes on. The digestive disruption from the GI damage from chemo goes on. This isn't like eating some bad pork and waiting for it to pass; this is a system, persistent problem. All we're doing is postponing the inevitable and making the problem more concentrated.
I am aware that slowing down an overproductive colon allows the hydrophilic nature of that system to draw a lot of the fluid out of the liquid stool that forms the diarrhea. This reduces dehydration and compacts what will eventually pass. So I see the benefit there. But in effect, this is still like fighting a flood by blocking the drain. The other end is still flooding.
So I am very reluctant to medicate to stop chemo-related diarrhea. Because whenever I do that, I almost always wind up feeling much worse for it than if I'd just let the storm pass naturally.
This has been another in my continuing series of commentaries on my chemo-induced toilet-based lifestyle.